The Indy Star reports that Donald Brown and Reggie Wayne could miss this weeks game for the Colts:

Neither Colts RB Donald Brown nor wide receiver Reggie Wayne practiced. Team president Bill Polian told NFL Network that while Brown is unlikely to play this week, Wayne probably would miss only a day or two of practice ahead of the San Francisco 49ers’ visit to Lucas Oil Stadium on Sunday. Like Brown, Wayne (strained groin) was hurt Sunday at St. Louis.